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Otherwise, it will be difficult tofind aspects that are notcovered byanyone and, onthecontrary, toselect materials fordevelopment, analysis, argumentation, comparison.
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Thenext stage is complex andconsists indefining goals, objectives, research methods, selection andsystematization ofrelevant literature andparallel drawing up ofathesis plan, which is apreliminary outline ofthestructure andcontent offuture student scientific work. When familiarizing with thesources ofinformation, one should take into account their novelty. Theperiods ofobsolescence ofeducational literature are established byorder oftheMinistry ofEducation andScience No. 1623 ofApril 11, 2001: forageneral humanitarian, socio-economic profile andspecial disciplines five years; forgeneral professional, natural science, mathematical subjects ten years. Themeasures ofrelevance do notrelate tosources ofin-depth fundamental study oftheissue. It does notstipulate theorder andterms after which research publications: articles, dissertations, reports, etc., are considered outdated, butuniversity regulatory controllers, when checking their thesis forcompliance with standards, are almost always guided bytherequirements set fortextbooks. Forinformational purposes, noone forbids using them, butinorder toavoid sending thefinished diploma forrevision, it is better toinclude only works noolder than five years inthelist ofused literature. InJanuary 2017, theorder oftheMinistry ofEducation andScience entered into force No. 1651, canceling theeffect oforders No. 1623 andNo. 133, which regulated theprovision ofuniversity libraries with scientific andeducational literature (it was inthem that theterms ofits obsolescence were prescribed). Thenew document aroused alot ofquestions from theexperts oftheacademic community, andtheofficial answers ofthedepartment tothem did notclarify thesituation, so teachers still prefer toadhere totheold standards, determining theexpiration date ofthesources used towrite thethesis. Algorithm ofwriting Thescheme ofwork onadiploma is standard forall students according toasingle algorithm, graduates who write both project andresearch FQPs go tofuture defense. First ofall, you need todecide onasupervisor, then choose atopic. It is approved before thestart ofthepre-diploma practice, towhich thestudent is sent with theassignment fortheFQP signed bythehead ofthedepartment.
Thestructure ofthethesis According tothegenerally accepted rules forwriting adiploma, its main part should consist ofthree chapters: First (atleast three paragraphs). Written onthebasis ofasynthesis andanalysis oftheoretical information gleaned from selected sources; reveals thecentral concepts, theessence ofaphenomenon orprocess, different points ofview ontheobject andsubject ofresearch. Second (atleast three subsections). Assigned tofactual material andanalysis oftheproblem; contains statistical information with quantitative andqualitative characteristics ofthephenomenon under consideration, astatement oftheidentified trends andshortcomings inits state anddevelopment. Third (theminimum number ofparagraphs is three). Dedicated todeveloping asolution toaproblem. His diploma student proposes onthebasis ofthesecond chapter with scientific justification, forwhich thetheoretical provisions ofthefirst are involved. Thechapters should be approximately equal inlength. Atthefinal stage, aconclusion, anintroduction, afinal list ofused literature are drawn up andablock with annexes is completed. How toproperly draw up athesis Instudent memos andontheir official websites, all universities must post detailed methodological recommendations containing requirements foradiploma. They indicate: volume how many pages inthediploma should be; structure how many chapters todivide thestudy, what towrite intheintroduction andconclusion; what materials should be included intheattachments andhow tonumber them; technical regulations where toput down, from which sheet tostart pagination, what font touse fortext andheadings, how toindent theparagraph andmargins, line spacing; thenumber ofsources inthebibliographic list; permissible percentage ofuniqueness when checking forplagiarism. Most universities andinstitutes include inmethodological collections: atemplate forthetitle page; forms ofreviews, annotations, reviews; sample bibliography; examples ofthedesign ofreferences, footnotes, formulas, tables, figures, diagrams, photos. It remains only tocarefully check with theuniversity standard andfollow therecommendations, since thenormative control will be meticulously carried out precisely according tothepoints ofthemanual, andonly then relying onGOSTs. Average requirements forathesis: Volume 50-70 pages, excluding attachments and, asarule, bibliography. Thenumber ofsources is atleast 40, and70% are publications notolder than five years. Thebibliographic list is drawn up inaccordance with GOST 7.80-2000, 7.1-2003, 7.0.5-2008, 7.0.1-2011. Times New Roman inblack, 14th fortext, 15th forsubheadings, 16th forheadings. Theinterval is 1.5. Margins atleast 2 cm totheleft, bottom andtop; 1.5 cm ontheright. Printing is only one-sided. Thestandard ofuniqueness ofthediploma: humanities 80%, exact 75%.
How tochoose acompany forwriting adiploma Checklist: Asolid site it should be akind ofInternet branch ofanofficially registered company with atleast one offline office; that is, thesite must be afull-fledged working tool, andnotaone-page business card onfree hosting. Theage ofthecompany is atleast 5 years. Only those who really know how towork can become aveteran ofthemarket. Conclusion ofanagreement thelists ofcustomers ofthecompany forwriting student papers are nottransferred tothedean's offices, do notworry. You need aconfirmation ofthedeal toensure that thework is done.
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Thenext stage is complex andconsists indefining goals, objectives, research methods, selection andsystematization ofrelevant literature andparallel drawing up ofathesis plan, which is apreliminary outline ofthestructure andcontent offuture student scientific work. When familiarizing with thesources ofinformation, one should take into account their novelty. Theperiods ofobsolescence ofeducational literature are established byorder oftheMinistry ofEducation andScience No. 1623 ofApril 11, 2001: forageneral humanitarian, socio-economic profile andspecial disciplines five years; forgeneral professional, natural science, mathematical subjects ten years. Themeasures ofrelevance do notrelate tosources ofin-depth fundamental study oftheissue. It does notstipulate theorder andterms after which research publications: articles, dissertations, reports, etc., are considered outdated, butuniversity regulatory controllers, when checking their thesis forcompliance with standards, are almost always guided bytherequirements set fortextbooks. Forinformational purposes, noone forbids using them, butinorder toavoid sending thefinished diploma forrevision, it is better toinclude only works noolder than five years inthelist ofused literature. InJanuary 2017, theorder oftheMinistry ofEducation andScience entered into force No. 1651, canceling theeffect oforders No. 1623 andNo. 133, which regulated theprovision ofuniversity libraries with scientific andeducational literature (it was inthem that theterms ofits obsolescence were prescribed). Thenew document aroused alot ofquestions from theexperts oftheacademic community, andtheofficial answers ofthedepartment tothem did notclarify thesituation, so teachers still prefer toadhere totheold standards, determining theexpiration date ofthesources used towrite thethesis. Algorithm ofwriting Thescheme ofwork onadiploma is standard forall students according toasingle algorithm, graduates who write both project andresearch FQPs go tofuture defense. First ofall, you need todecide onasupervisor, then choose atopic. It is approved before thestart ofthepre-diploma practice, towhich thestudent is sent with theassignment fortheFQP signed bythehead ofthedepartment.
Thestructure ofthethesis According tothegenerally accepted rules forwriting adiploma, its main part should consist ofthree chapters: First (atleast three paragraphs). Written onthebasis ofasynthesis andanalysis oftheoretical information gleaned from selected sources; reveals thecentral concepts, theessence ofaphenomenon orprocess, different points ofview ontheobject andsubject ofresearch. Second (atleast three subsections). Assigned tofactual material andanalysis oftheproblem; contains statistical information with quantitative andqualitative characteristics ofthephenomenon under consideration, astatement oftheidentified trends andshortcomings inits state anddevelopment. Third (theminimum number ofparagraphs is three). Dedicated todeveloping asolution toaproblem. His diploma student proposes onthebasis ofthesecond chapter with scientific justification, forwhich thetheoretical provisions ofthefirst are involved. Thechapters should be approximately equal inlength. Atthefinal stage, aconclusion, anintroduction, afinal list ofused literature are drawn up andablock with annexes is completed. How toproperly draw up athesis Instudent memos andontheir official websites, all universities must post detailed methodological recommendations containing requirements foradiploma. They indicate: volume how many pages inthediploma should be; structure how many chapters todivide thestudy, what towrite intheintroduction andconclusion; what materials should be included intheattachments andhow tonumber them; technical regulations where toput down, from which sheet tostart pagination, what font touse fortext andheadings, how toindent theparagraph andmargins, line spacing; thenumber ofsources inthebibliographic list; permissible percentage ofuniqueness when checking forplagiarism. Most universities andinstitutes include inmethodological collections: atemplate forthetitle page; forms ofreviews, annotations, reviews; sample bibliography; examples ofthedesign ofreferences, footnotes, formulas, tables, figures, diagrams, photos. It remains only tocarefully check with theuniversity standard andfollow therecommendations, since thenormative control will be meticulously carried out precisely according tothepoints ofthemanual, andonly then relying onGOSTs. Average requirements forathesis: Volume 50-70 pages, excluding attachments and, asarule, bibliography. Thenumber ofsources is atleast 40, and70% are publications notolder than five years. Thebibliographic list is drawn up inaccordance with GOST 7.80-2000, 7.1-2003, 7.0.5-2008, 7.0.1-2011. Times New Roman inblack, 14th fortext, 15th forsubheadings, 16th forheadings. Theinterval is 1.5. Margins atleast 2 cm totheleft, bottom andtop; 1.5 cm ontheright. Printing is only one-sided. Thestandard ofuniqueness ofthediploma: humanities 80%, exact 75%.
How tochoose acompany forwriting adiploma Checklist: Asolid site it should be akind ofInternet branch ofanofficially registered company with atleast one offline office; that is, thesite must be afull-fledged working tool, andnotaone-page business card onfree hosting. Theage ofthecompany is atleast 5 years. Only those who really know how towork can become aveteran ofthemarket. Conclusion ofanagreement thelists ofcustomers ofthecompany forwriting student papers are nottransferred tothedean's offices, do notworry. You need aconfirmation ofthedeal toensure that thework is done.
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Astudy published intheBritish Medical Journal ofSports Medicine onMarch 29, 2021, estimates that physical inactivity is responsible for7.2% ofall-cause deaths each year. This represents about 4 million deaths out ofanaverage of56.9 million peryear. TheAmerican andCanadian researchers behind this work obtained information from several databases indifferent states. Inaddition, they tried toget theresults closest toreality byconsidering pathologies whose causal relationship with asedentary lifestyle is well known. Inother words, we are talking about aserious level ofevidence. According totheresults, indeveloping countries, most deaths (inabsolute numbers) occur due tothelack ofphysical activity ofapart oftheir population. Ontheother hand, developed countries are more likely tosuffer from theeffects ofasedentary lifestyle, asthey are subject toamuch higher percentage ofdeaths. Thestudy's authors strongly believe that thepublic health burden associated with physical inactivity is aglobal problem that will require international cooperation tomobilize change andachieve these public health goals. Forresearchers, change should be focused onachieving public health goals. This means increased investment inthere-opening ofsports facilities during thepandemic. It also means making them available toasmany people aspossible inthelong run.
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According toarecent study, lack ofphysical activity is themain risk factor forpremature mortality fortheentire world population.
This paper highlights thepercentage ofdeaths that can be attributed tosedentary lifestyles worldwide. Analarming conclusion is that asedentary lifestyle is themain risk factor formany non-communicable diseases. These include cardiovascular disease, coronary artery disease, stroke, hypertension, andtype 2 diabetes. There are also cancers (bladder, stomach, kidney, breast, colon, andesophagus), depression, anddementia.
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Astudy published intheBritish Medical Journal ofSports Medicine onMarch 29, 2021, estimates that physical inactivity is responsible for7.2% ofall-cause deaths each year. This represents about 4 million deaths out ofanaverage of56.9 million peryear. TheAmerican andCanadian researchers behind this work obtained information from several databases indifferent states. Inaddition, they tried toget theresults closest toreality byconsidering pathologies whose causal relationship with asedentary lifestyle is well known. Inother words, we are talking about aserious level ofevidence. According totheresults, indeveloping countries, most deaths (inabsolute numbers) occur due tothelack ofphysical activity ofapart oftheir population. Ontheother hand, developed countries are more likely tosuffer from theeffects ofasedentary lifestyle, asthey are subject toamuch higher percentage ofdeaths. Thestudy's authors strongly believe that thepublic health burden associated with physical inactivity is aglobal problem that will require international cooperation tomobilize change andachieve these public health goals. Forresearchers, change should be focused onachieving public health goals. This means increased investment inthere-opening ofsports facilities during thepandemic. It also means making them available toasmany people aspossible inthelong run.
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Stress often causes bacteria toform biofilms. Stress can manifest asaphysical barrier, ultraviolet light, oratoxic substance such asantibiotics. Theformation ofthese biofilms takes from several hours todays, andthey can be ofdifferent shapes, sizes, colors, andtextures depending onthetype ofbacteria. Being inabiofilm state protects them from harmful substances intheenvironment biofilms have aunique outer wall with different physical andchemical properties than their individual cells. They can coordinate metabolism, slow down their growth, andeven form animpenetrable barrier ofwrinkles andcreases. This is one oftheways they achieve high antibiotic resistance. Researchers from theUnited Kingdom recently studied thetransition oftheHay Bacillus bacterium from afree-moving swarm toabiofilm asadefense mechanism andpublished what they did tocombat its antibiotic-resistant properties ineLife.

Todetermine if their test strain was behaving like theothers, they first ran stress tests onthem. They tested thebacteria's response tothephysical barrier, ultraviolet light, andantibiotics. Theaddition ofaphysical barrier led tothetransition ofbacteria from one layer toamultilayer layer, followed byanincrease incell density andtheformation ofmultilayer islands near thebarrier. Later, wrinkles formed ontheislands near thebarrier intheplace where they began toappear initially.
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When they applied ultraviolet light totheswarm, they again observed adrop incell speed andanincrease indensity. Andafter thescientists added alarge dose oftheantibiotic kanamycin, thebacterial cells formed abiofilm. Theresearchers then developed astrategy tocombat this bacterial biofilm. They added kanamycin totheenvironment ofanew batch ofswarming bacterial cells andwatched asthebiofilm began toform. They then re-injected theantibiotic atamuch higher dose than thefirst, just before thebiofilm formation was complete. Asaresult, thepartially formed biofilm was destroyed andbacterial cells died. This shows that antibiotic-resistant bacteria lose their resistance toantibiotics when they undergo aphase transition, right before going into thebiofilm, where they will become much more resistant. Thus, with thecorrect administration ofantibiotics, thebacteria can be attacked intheir most vulnerable state anddestroyed. Theresearchers believe that similar transitions from swarm tobiofilm occur inother bacterial species. Their research may pave theway forfinding more effective ways tocontrol clinically relevant bacteria. Forexample, Salmonella enterica, which spreads into thebloodstream andis transmitted through contaminated food. OrPseudomonas aeruginosa with multiple drug resistance, which after surgery causes infections intheblood, lungs (pneumonia) andother parts ofthebody andspreads inhospitals.
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Stress often causes bacteria toform biofilms. Stress can manifest asaphysical barrier, ultraviolet light, oratoxic substance such asantibiotics. Theformation ofthese biofilms takes from several hours todays, andthey can be ofdifferent shapes, sizes, colors, andtextures depending onthetype ofbacteria. Being inabiofilm state protects them from harmful substances intheenvironment biofilms have aunique outer wall with different physical andchemical properties than their individual cells. They can coordinate metabolism, slow down their growth, andeven form animpenetrable barrier ofwrinkles andcreases. This is one oftheways they achieve high antibiotic resistance. Researchers from theUnited Kingdom recently studied thetransition oftheHay Bacillus bacterium from afree-moving swarm toabiofilm asadefense mechanism andpublished what they did tocombat its antibiotic-resistant properties ineLife.

Todetermine if their test strain was behaving like theothers, they first ran stress tests onthem. They tested thebacteria's response tothephysical barrier, ultraviolet light, andantibiotics. Theaddition ofaphysical barrier led tothetransition ofbacteria from one layer toamultilayer layer, followed byanincrease incell density andtheformation ofmultilayer islands near thebarrier. Later, wrinkles formed ontheislands near thebarrier intheplace where they began toappear initially.
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When they applied ultraviolet light totheswarm, they again observed adrop incell speed andanincrease indensity. Andafter thescientists added alarge dose oftheantibiotic kanamycin, thebacterial cells formed abiofilm. Theresearchers then developed astrategy tocombat this bacterial biofilm. They added kanamycin totheenvironment ofanew batch ofswarming bacterial cells andwatched asthebiofilm began toform. They then re-injected theantibiotic atamuch higher dose than thefirst, just before thebiofilm formation was complete. Asaresult, thepartially formed biofilm was destroyed andbacterial cells died. This shows that antibiotic-resistant bacteria lose their resistance toantibiotics when they undergo aphase transition, right before going into thebiofilm, where they will become much more resistant. Thus, with thecorrect administration ofantibiotics, thebacteria can be attacked intheir most vulnerable state anddestroyed. Theresearchers believe that similar transitions from swarm tobiofilm occur inother bacterial species. Their research may pave theway forfinding more effective ways tocontrol clinically relevant bacteria. Forexample, Salmonella enterica, which spreads into thebloodstream andis transmitted through contaminated food. OrPseudomonas aeruginosa with multiple drug resistance, which after surgery causes infections intheblood, lungs (pneumonia) andother parts ofthebody andspreads inhospitals.
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